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The Office of Research Integrity (ORI) oversees Public Health Service (PHS) research integrity activities, excluding FDA-related tasks. As part of the U.S. Department of Health and Human Services (HHS), ORI focuses on detecting, investigating, and preventing research misconduct. It monitors investigations, recommends actions, assists with appeals, and provides technical support to institutions. ORI also promotes responsible conduct of research through policies, education, and evaluations, while managing whistleblower protections and responding to Freedom of Information Act requests.